300349-97-7

300349-97-7 structure

Name: cpm-1285
Chemical Name: cpm-1285
CAS Number: 300349-97-7
Molecular Formula: C₁₅₃H₂₄₀N₄₄O₄₂S
Molecular Weight: 3399.88
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-03-08 11:17:28
Modify Date: 2024-03-08 11:17:28
cpm-1285 induces apoptosis by functionally blocking intracellular Bcl-2 and related death antagonists. cpm-1285 shows strong binding potency to Bcl-2 with an IC50 value of 130 nM. cpm-1285 reduces tumor burden in mice[1].

Name	cpm-1285

Description	cpm-1285 induces apoptosis by functionally blocking intracellular Bcl-2 and related death antagonists. cpm-1285 shows strong binding potency to Bcl-2 with an IC50 value of 130 nM. cpm-1285 reduces tumor burden in mice[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Wang JL, et al. Cell permeable Bcl-2 binding peptides: a chemical approach to apoptosis induction in tumor cells. Cancer Res. 2000 Mar 15;60(6):1498-502.

Molecular Formula	C₁₅₃H₂₄₀N₄₄O₄₂S
Molecular Weight	3399.88