207399-56-2

207399-56-2 structure

Name: Anticancer agent 168
Chemical Name: Anticancer agent 168
CAS Number: 207399-56-2
Molecular Formula: C₁₆H₁₁ClN₂O₆
Molecular Weight: 362.72
Catalog: Research Areas Cancer
Create Date: 2024-01-09 11:00:19
Modify Date: 2025-08-25 17:01:21
Anticancer agent 168 (compound d16) is a inhibitor of DNA2. Anticancer agent 168 induces apoptosis and cell-cycle arrest mainly at S-phase, and exhibits anticancer activities and overcomes chemotherapy resistance in mutp53-bearing cancers[1].

Name	Anticancer agent 168

Description	Anticancer agent 168 (compound d16) is a inhibitor of DNA2. Anticancer agent 168 induces apoptosis and cell-cycle arrest mainly at S-phase, and exhibits anticancer activities and overcomes chemotherapy resistance in mutp53-bearing cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Folly-Kossi H, et al. DNA2 Nuclease Inhibition Confers Synthetic Lethality in Cancers with Mutant p53 and Synergizes with PARP Inhibitors. Cancer Res Commun. 2023;3(10):2096-2112.

Molecular Formula	C₁₆H₁₁ClN₂O₆
Molecular Weight	362.72