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2287186-66-5

2287186-66-5 structure
2287186-66-5 structure
  • Name: ABBV-467
  • Chemical Name: ABBV-467
  • CAS Number: 2287186-66-5
  • Molecular Formula: C53H51Cl2FN6O9S
  • Molecular Weight: 1037.98
  • Catalog: Signaling Pathways Apoptosis Bcl-2 Family
  • Create Date: 2024-03-18 16:46:04
  • Modify Date: 2024-03-18 16:46:04
  • ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). ABBV-467 induces apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1].
Name ABBV-467
Description ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). ABBV-467 induces apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1].
Related Catalog
Target

MCL-1[1].

References

[1]. Yuda J, et al. Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients. Commun Med (Lond). 2023 Oct 25;3(1):154.  

Molecular Formula C53H51Cl2FN6O9S
Molecular Weight 1037.98

Chemsrc provides CAS#:2287186-66-5 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 2287186-66-5 | Chemsrc address: https://www.chemsrc.com/en/baike/1815577.html

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