78756-33-9

78756-33-9 structure

78756-33-9 structure

Name: Flumazenil Impurity F
Chemical Name: Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]b enzodiazepine-3-carboxylate
CAS Number: 78756-33-9
Molecular Formula: C₁₅H₁₄ClN₃O₃
Molecular Weight: 319.74300
Create Date: 2018-12-27 16:41:18
Modify Date: 2024-01-18 18:21:38

Name	Ethyl 8-chloro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]b enzodiazepine-3-carboxylate
Synonyms	Ethyl 8-chloro-1-ethyl-4-oxo-4H-quinolizine-3-carboxylate ethyl 8-chloro-1-ethyl-4H-quinolizin-4-one-3-carboxylate Flumazenil Impurity F

Density	1.43g/cm3
Boiling Point	554ºC at 760 mmHg
Molecular Formula	C₁₅H₁₄ClN₃O₃
Molecular Weight	319.74300
Flash Point	288.9ºC
Exact Mass	319.07200
PSA	64.43000
LogP	2.22590
Index of Refraction	1.658

2999-46-4 structure

2999-46-4

~46%

78756-33-9 structure

78756-33-9

Literature: WiSys Technology Foundation, Inc. Patent: US2006/258643 A1, 2006 ; Location in patent: Page/Page column 31-32 ; US 20060258643 A1

2999-46-4 structure

2999-46-4

865-47-4 structure

865-47-4

814-49-3 structure

814-49-3

5973-29-5 structure

5973-29-5

~%

Detail

Literature: Hoffman-La Roche Inc. Patent: US4316839 A1, 1982 ;

2999-46-4 structure

2999-46-4

1027918-09-7 structure

1027918-09-7

~%

78756-33-9 structure

78756-33-9

Literature: Yang, Jie; Teng, Yun; Ara, Shamim; Rallapalli, Sundari; Cook, James M. Synthesis, 2009 , # 6 art. no. M05108SS, p. 1036 - 1040

5973-29-5 structure

5973-29-5

~%

78756-33-9 structure

78756-33-9

Literature: Gu, Zi-Qiang; Wong, Garry; Dominguez, Celia; Costa, Brian R. de; Rice, Kenner C.; Skolnick, Phil Journal of Medicinal Chemistry, 1993 , vol. 36, # 8 p. 1001 - 1006

2999-46-4 structure

2999-46-4

5973-29-5 structure

5973-29-5

~%

78756-33-9 structure

78756-33-9

Literature: Watjen, Frank; Baker, Raymond; Engelstoff, Mogens; Herbert, Richard; MacLeod, Angus; et al. Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2282 - 2291

Precursor 4
2999-46-4 865-47-4 814-49-3 5973-29-5
DownStream 0