1417795-25-5

1417795-25-5 structure
1417795-25-5 structure
  • Name: TINK-IN-1
  • Chemical Name: TINK-IN-1
  • CAS Number: 1417795-25-5
  • Molecular Formula: C24H24N4O3
  • Molecular Weight: 416.47
  • Catalog: Research Areas Cancer
  • Create Date: 2024-09-20 15:28:39
  • Modify Date: 2024-09-20 15:28:39
  • TINK-IN-1 (Compound 9) is a potent and selective Traf2- and Nck-interacting kinase (TNIK) inhibitor with an IC50 of 8 nM. TINK-IN-1 inhibits colorectal cancer cells viability[1].

Name TINK-IN-1
Description TINK-IN-1 (Compound 9) is a potent and selective Traf2- and Nck-interacting kinase (TNIK) inhibitor with an IC50 of 8 nM. TINK-IN-1 inhibits colorectal cancer cells viability[1].
Related Catalog
Target

IC50: 8 nM (TNIK), 4.7 μM (hERG), 6.3 μM (β-lactamase)[1]

References

[1]. Ho KK, et al. Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors. Bioorg Med Chem Lett. 2013 Jan 15;23(2):569-73.

Molecular Formula C24H24N4O3
Molecular Weight 416.47
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