Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GPX4-IN-5
Price: Check
Purity: 99.58%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2922824-09-5

2922824-09-5 structure

2922824-09-5 structure

Name: GPX4-IN-5
Chemical Name: GPX4-IN-5
CAS Number: 2922824-09-5
Molecular Formula: C₁₈H₁₇ClFNO₅
Molecular Weight: 381.78
Catalog: Signaling Pathways Apoptosis Ferroptosis
Create Date: 2024-04-09 14:54:39
Modify Date: 2024-04-09 14:54:39
GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM. GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].

Name	GPX4-IN-5

Description	GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM. GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis
Target	IC50: 0.12 μM (GPX4)[1]
References	[1]. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.

Molecular Formula	C₁₈H₁₇ClFNO₅
Molecular Weight	381.78