2648418-86-2

2648418-86-2 structure

Name: DGKα-IN-3
Chemical Name: DGKα-IN-3
CAS Number: 2648418-86-2
Molecular Formula: C₂₆H₂₇F₃N₄O₃
Molecular Weight: 500.51
Catalog: Research Areas Cancer
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DGKα-IN-3 (example 25) is a DGKα inhibitor with the IC50 of 283 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.

Name	DGKα-IN-3

Description	DGKα-IN-3 (example 25) is a DGKα inhibitor with the IC50 of 283 nM, extracted from patent WO2021105115. DGKα-IN-2 significantly enhances the anti-tumor effect of anti-PD-1 by increasing the proliferation and function of T cells. DGKα-IN-2 has the potential for cancer and immunology study.
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	283 nM (DGKα)
References	[1]. Schmees, Norbert, et al. Preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. WO2021105115.

Molecular Formula	C₂₆H₂₇F₃N₄O₃
Molecular Weight	500.51