2925814-05-5

2925814-05-5 structure

Name: Antiproliferative agent-32
Chemical Name: Antiproliferative agent-32
CAS Number: 2925814-05-5
Molecular Formula: C₁₉H₁₅NO₂
Molecular Weight: 289.33
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-10-11 14:28:05
Modify Date: 2024-10-11 14:28:05
Antiproliferative agent-32 (Compound 1c) inhibits the phosphorylation of PI3K/Akt/mTOR signaling pathway. Antiproliferative agent-32 inhibits Huh7 and SK-Hep-1 cells proliferation, and induce cells apoptosis, causes mitochondrial damage. Antiproliferative agent-32 can be used for research of hepatocellular carcinoma[1].

Name	Antiproliferative agent-32

Description	Antiproliferative agent-32 (Compound 1c) inhibits the phosphorylation of PI3K/Akt/mTOR signaling pathway. Antiproliferative agent-32 inhibits Huh7 and SK-Hep-1 cells proliferation, and induce cells apoptosis, causes mitochondrial damage. Antiproliferative agent-32 can be used for research of hepatocellular carcinoma[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Wang Y, et al. Design, synthesis, and biological evaluation of 1-styrenyl isoquinoline derivatives for anti-hepatocellular carcinoma activity and effect on mitochondria. Eur J Med Chem. 2023 Aug 5;256:115420.

Molecular Formula	C₁₉H₁₅NO₂
Molecular Weight	289.33