2925307-53-3

2925307-53-3 structure

Name: Antifungal agent 68
Chemical Name: Antifungal agent 68
CAS Number: 2925307-53-3
Molecular Formula: C₂₃H₂₇ClN₂O₃
Molecular Weight: 414.93
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2024-04-06 13:22:05
Modify Date: 2024-04-06 13:22:05
Antifungal agent 68 (compound 10) is an antifungal agent against Candida and Cryptococcus gattii. Antifungal agent 68 inhibits fungal ergosterol biosynthesis, possibly by targeting lanosterol 14α-demethylase (CYP51). There is an interaction between the imidazole ring of antifungal agent 68 and the heme group of CYP51[1].

Name	Antifungal agent 68

Description	Antifungal agent 68 (compound 10) is an antifungal agent against Candida and Cryptococcus gattii. Antifungal agent 68 inhibits fungal ergosterol biosynthesis, possibly by targeting lanosterol 14α-demethylase (CYP51). There is an interaction between the imidazole ring of antifungal agent 68 and the heme group of CYP51[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Campos Péret VA, et al. New miconazole-based azoles derived from eugenol show activity against Candida spp. and Cryptococcus gattii by inhibiting the fungal ergosterol biosynthesis. Eur J Med Chem. 2023 Aug 5;256:115436..

Molecular Formula	C₂₃H₂₇ClN₂O₃
Molecular Weight	414.93