2413127-32-7

2413127-32-7 structure

Name: Anti-inflammatory agent 56
Chemical Name: Anti-inflammatory agent 56
CAS Number: 2413127-32-7
Molecular Formula: C₂₁H₁₅F₃N₄O₄S
Molecular Weight: 476.43
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2023-11-06 17:45:59
Modify Date: 2024-01-10 17:31:47
Anti-inflammatory agent 56 (Compound 9) is a selective COX-2 inhibitor (IC50: 0.54 μM). Anti-inflammatory agent 56 has anti-oxidant and anti-inflammatory effects. Anti-inflammatory agent 56 inhibits oxidative stress induced cell death. Anti-inflammatory agent 56 inhibits oxidative stress and neuroinflammation by inhibiting Keap1, COX-2 and iNOS. Anti-inflammatory agent 56 has low acute toxicity in mice (LD50: 1000 mg/kg)[1].

Name	Anti-inflammatory agent 56

Description	Anti-inflammatory agent 56 (Compound 9) is a selective COX-2 inhibitor (IC50: 0.54 μM). Anti-inflammatory agent 56 has anti-oxidant and anti-inflammatory effects. Anti-inflammatory agent 56 inhibits oxidative stress induced cell death. Anti-inflammatory agent 56 inhibits oxidative stress and neuroinflammation by inhibiting Keap1, COX-2 and iNOS. Anti-inflammatory agent 56 has low acute toxicity in mice (LD50: 1000 mg/kg)[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2
References	[1]. Wang Y, et al. Synthesis of 1,3,5-triphenyl-1,2,4-triazole derivatives and their neuroprotection by anti-oxidative stress and anti-inflammation and protecting BBB. Eur J Med Chem. 2023 Nov 15;260:115742.

Molecular Formula	C₂₁H₁₅F₃N₄O₄S
Molecular Weight	476.43