2559759-59-8

2559759-59-8 structure

Name: ABCG2-IN-2
Chemical Name: ABCG2-IN-2
CAS Number: 2559759-59-8
Molecular Formula: C₂₅H₃₄N₄O₄
Molecular Weight: 454.56
Catalog: Signaling Pathways Membrane Transporter/Ion Channel BCRP
Create Date: 2023-11-04 19:53:50
Modify Date: 2024-01-27 23:33:41
ABCG2-IN-2 is a potent ABCG2 inhibitor with favorable oral pharmacokinetic profiles in mice. ABCG2-IN-2 can be used for the research of tumor multidrug resistance (MDR) and erythropoietic protoporphyria (EPP)[1].

Name	ABCG2-IN-2

Description	ABCG2-IN-2 is a potent ABCG2 inhibitor with favorable oral pharmacokinetic profiles in mice. ABCG2-IN-2 can be used for the research of tumor multidrug resistance (MDR) and erythropoietic protoporphyria (EPP)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> BCRP
References	[1]. Zhu J, et al. Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors. Eur J Med Chem. 2023 Nov 5;259:115666. doi: 10.1016/j.ejmech.2023.115666. Epub 2023 Jul 20.

Molecular Formula	C₂₅H₃₄N₄O₄
Molecular Weight	454.56