24900-61-6

24900-61-6 structure

Name: hPL-IN-2
Chemical Name: hPL-IN-2
CAS Number: 24900-61-6
Molecular Formula: C₁₉H₁₁Cl₄NO₃
Molecular Weight: 443.11
Catalog: Research Areas Metabolic Disease
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hPL-IN-2 (compound 2u) is a potent, reversible, and non-competitive inhibitor of pancreatic lipase (IC50: 1.63 μM) and can be used in anti-obesity research[1].

Name	hPL-IN-2

Description	hPL-IN-2 (compound 2u) is a potent, reversible, and non-competitive inhibitor of pancreatic lipase (IC50: 1.63 μM) and can be used in anti-obesity research[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	IC50: 1.63 μM (Pancreatic lipase, PL); Ki：1.7 μM (human PL)[1]
References	[1]. Zhao Y, et al. Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase. Bioorg Med Chem. 2023 Aug 15;91:117413..