915315-44-5
915315-44-5 structure
- Name: cephalandole B
- Chemical Name: Cephalandole B
- CAS Number: 915315-44-5
- Molecular Formula: C17H14N2O3
- Molecular Weight: 294.3
- Create Date: 2024-02-04 12:42:20
- Modify Date: 2025-08-25 19:31:13
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cephalandole B, an indole alkaloid isolated from cyanide, significantly inhibited IL-17A gene expression and suppressed IL-17A luciferase reporter in Jukat cells in a dose-dependent manner.
| Name | Cephalandole B |
|---|
| Description | cephalandole B, an indole alkaloid isolated from cyanide, significantly inhibited IL-17A gene expression and suppressed IL-17A luciferase reporter in Jukat cells in a dose-dependent manner. |
|---|---|
| In Vitro | Two indole alkaloids, including one new indigodole D and cephalandole B, were isolated from Qing Dai. Cephalandole B did not inhibit the IL-17A protein secretion. Nevertheless, both isolates notably inhibited IL-17A gene expression, especially cephalandole B, in a dose-dependent manner in Jukat cells with IL-17A luciferase reporter.[1] |
| References | 1. Lee CL, et al. IL-17A inhibitions of indole alkaloids from traditional Chinese medicine Qing Dai. J Ethnopharmacol. 2020;255:112772. |
| Molecular Formula | C17H14N2O3 |
|---|---|
| Molecular Weight | 294.3 |