220386-65-2
220386-65-2 structure
- Name: UR-3216
- Chemical Name: UR-3216
- CAS Number: 220386-65-2
- Molecular Formula: C27H29N7O7
- Molecular Weight: 563.56
- Catalog: Signaling Pathways Cytoskeleton Integrin
- Create Date: 2024-04-06 10:21:09
- Modify Date: 2024-04-06 10:21:09
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UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < 1 nM). UR-2992, the active form of UR-3216, binds to platelets for a long period of time, while the unbound drug is rapidly cleared.
| Name | UR-3216 |
|---|
| Description | UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < 1 nM). UR-2992, the active form of UR-3216, binds to platelets for a long period of time, while the unbound drug is rapidly cleared. |
|---|---|
| References | 1. Aga Y, Baba K, Tam S, Nakanishi T, Yoneda K, Kita J, Ueno H. UR-3216: a new generation oral platelet GPIIb/IIIa antagonist. Curr Pharm Des. 2004;10(14):1597-601. Review. PubMed PMID: 15134558. |
| Molecular Formula | C27H29N7O7 |
|---|---|
| Molecular Weight | 563.56 |