1037826-43-9
1037826-43-9 structure
- Name: A-933548
- Chemical Name: A-933548
- CAS Number: 1037826-43-9
- Molecular Formula: C25H21N5O3
- Molecular Weight: 439.47
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Proteasome
- Create Date: 2024-04-08 18:00:10
- Modify Date: 2024-04-08 18:00:10
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A-933548 is a potent Calpain inhibitor. A-933548 features enhanced selectivity versus related cysteine protease cathepsins, favorable microsomal stability, and efficacy in cellular assays.
| Name | A-933548 |
|---|
| Description | A-933548 is a potent Calpain inhibitor. A-933548 features enhanced selectivity versus related cysteine protease cathepsins, favorable microsomal stability, and efficacy in cellular assays. |
|---|---|
| References | 1. Kling A, Jantos K, Mack H, Hornberger W, Drescher K, Nimmrich V, Relo A, Wicke K, Hutchins CW, Lao Y, Marsh K, Moeller A. Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer's Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides. J Med Chem. 2017 Aug 24;60(16):7123-7138. doi: 10.1021/acs.jmedchem.7b00731. Epub 2017 Aug 15. PubMed PMID: 28759231. |
| Molecular Formula | C25H21N5O3 |
|---|---|
| Molecular Weight | 439.47 |