2945983-00-4

2945983-00-4 structure

Name: TS-IN-2
Chemical Name: TS-IN-2
CAS Number: 2945983-00-4
Molecular Formula: C₁₈H₂₃N₃O₄S
Molecular Weight: 377.46
Catalog: Signaling Pathways Apoptosis Thymidylate Synthase
Create Date: 2023-09-28 16:07:56
Modify Date: 2024-04-06 11:00:28
TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage[1].

Name	TS-IN-2

Description	TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Thymidylate Synthase Research Areas >> Cancer
References	[1]. Syed Nazreen, et al. New Natural Eugenol Derivatives as Antiproliferative Agents: Synthesis, Biological Evaluation, and Computational Studies. ACS Omega. 2023 May 15;8(21):18811-18822.

Molecular Formula	C₁₈H₂₃N₃O₄S
Molecular Weight	377.46