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876625-29-5

876625-29-5 structure

876625-29-5 structure

Name: S07-1066
Chemical Name: S07-1066
CAS Number: 876625-29-5
Molecular Formula: C₁₆H₁₁Cl₂FO₂
Molecular Weight: 325.16
Catalog: Research Areas Cancer
Create Date: 2023-10-06 18:46:42
Modify Date: 2025-08-27 01:56:39
S07-1066 is an aldo-keto reductase 1C3 (AKR1C3) inhibitor, synergizing doxorubicin (DOX) cytotoxicity. S07-1066 selectively blocks AKR1C3-mediated reduction of DOX, and reverses the DOX resistance in overexpressing AKR1C3 cells[1].

Name	S07-1066

Description	S07-1066 is an aldo-keto reductase 1C3 (AKR1C3) inhibitor, synergizing doxorubicin (DOX) cytotoxicity. S07-1066 selectively blocks AKR1C3-mediated reduction of DOX, and reverses the DOX resistance in overexpressing AKR1C3 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	AKR1C3[1]
References	[1]. He S, et al. Development of Biaryl-Containing Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors for Reversing AKR1C3-Mediated Drug Resistance in Cancer Treatment. J Med Chem. 2023 Jul 6.

Molecular Formula	C₁₆H₁₁Cl₂FO₂
Molecular Weight	325.16

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