2479961-46-9
2479961-46-9 structure
- Name: RET-IN-23
- Chemical Name: RET-IN-23
- CAS Number: 2479961-46-9
- Molecular Formula: C28H28FN11
- Molecular Weight: 537.59
- Catalog: Research Areas Cancer
- Create Date: 2023-10-22 16:43:08
- Modify Date: 2026-03-05 18:46:19
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RET-IN-23 (compound 17) is a potent and orally active RET inhibitor with IC50 values of 1.32, 2.50, 6.54, 1.03, 1.47 nM for RET-WT, RET-CCDC6, RET-V804L, RET-V804M, RET-M918T, respectively. RET-IN-23 shows anti-tumor activity[1].
| Name | RET-IN-23 |
|---|
| Description | RET-IN-23 (compound 17) is a potent and orally active RET inhibitor with IC50 values of 1.32, 2.50, 6.54, 1.03, 1.47 nM for RET-WT, RET-CCDC6, RET-V804L, RET-V804M, RET-M918T, respectively. RET-IN-23 shows anti-tumor activity[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1.32 nM (RET-WT); 2.50 nM (RET-CCDC6); 6.54 nM (RET-V804L); 1.03 nM (RET-V804M); 1.47 nM (RET-M918T)[1]. |
| References |
| Molecular Formula | C28H28FN11 |
|---|---|
| Molecular Weight | 537.59 |