188240-41-7

188240-41-7 structure

Name: Maurotoxin
Chemical Name: Maurotoxin
CAS Number: 188240-41-7
Molecular Formula: C₁₄₅H₂₃₂N₄₆O₄₆S₈
Molecular Weight: 3612.19
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
Create Date: 2023-09-18 18:46:37
Modify Date: 2024-01-29 11:51:53
Maurotoxin is a 34-residue and four disulde-bridged toxin that can be isolated from the chactoid scorpion (Scorpio maurus). Maurotoxin inhibits the Shaker potassium channels (ShB) K+ current with an IC50 of 2 nM[1][2].

Name	Maurotoxin

Description	Maurotoxin is a 34-residue and four disulde-bridged toxin that can be isolated from the chactoid scorpion (Scorpio maurus). Maurotoxin inhibits the Shaker potassium channels (ShB) K+ current with an IC50 of 2 nM[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
References	[1]. Bende NS, et al. A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nat Commun. 2014 Jul 11;5:4350. [2]. Castle NA, et al. Maurotoxin: a potent inhibitor of intermediate conductance Ca2+-activated potassium channels. Mol Pharmacol. 2003 Feb;63(2):409-18.

Molecular Formula	C₁₄₅H₂₃₂N₄₆O₄₆S₈
Molecular Weight	3612.19