2948772-71-0

2948772-71-0 structure

Name: IDO1/TDO-IN-6
Chemical Name: IDO1/TDO-IN-6
CAS Number: 2948772-71-0
Molecular Formula: C₂₀H₁₇NO₅
Molecular Weight: 351.35
Catalog: Signaling Pathways Metabolic Enzyme/Protease Indoleamine 2,3-Dioxygenase (IDO)
Create Date: 2023-09-21 00:20:13
Modify Date: 2024-01-24 12:51:50
IDO1/TDO-IN-6 (compound 11) is a dual inhibitor of IDO1/TDO with IC50s of 2.25 and 2.89 μM, respectively. IDO1/TDO-IN-6 has inhibitory effects on IDO1 and TDO, with Ki values of 1.9 and 3.1 μM, respectively. IDO1/TDO-IN-6 can be used in cancer and immunology research[1].

Name	IDO1/TDO-IN-6

Description	IDO1/TDO-IN-6 (compound 11) is a dual inhibitor of IDO1/TDO with IC50s of 2.25 and 2.89 μM, respectively. IDO1/TDO-IN-6 has inhibitory effects on IDO1 and TDO, with Ki values of 1.9 and 3.1 μM, respectively. IDO1/TDO-IN-6 can be used in cancer and immunology research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Research Areas >> Inflammation/Immunology
References	[1]. Mei-Fen Bao, et al. Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens. Phytochemistry. 2023, 214:113794.

Molecular Formula	C₂₀H₁₇NO₅
Molecular Weight	351.35