2725863-08-9

2725863-08-9 structure

Name: COX-2-IN-32
Chemical Name: COX-2-IN-32
CAS Number: 2725863-08-9
Molecular Formula: C₂₅H₂₄O₆
Molecular Weight: 420.45
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2023-10-05 15:46:46
Modify Date: 2024-02-04 18:55:55
COX-2-IN-32 (Compound 2f) is an iNOS and COX-2 inhibitor. COX-2-IN-32 decreases the expression of NF-κB. COX-2-IN-32 has anti-inflammatory activity by inhibits NO production in LPS-induced RAW264.7 macrophages (IC50: 11.2 μM)[1].

Name	COX-2-IN-32

Description	COX-2-IN-32 (Compound 2f) is an iNOS and COX-2 inhibitor. COX-2-IN-32 decreases the expression of NF-κB. COX-2-IN-32 has anti-inflammatory activity by inhibits NO production in LPS-induced RAW264.7 macrophages (IC50: 11.2 μM)[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2
References	[1]. Emam SH, et al. Design and synthesis of methoxyphenyl- and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS-induced RAW264.7 macrophage cells. Bioorg Chem. 2021 Feb;107:104630.

Molecular Formula	C₂₅H₂₄O₆
Molecular Weight	420.45