884469-67-4

884469-67-4 structure

Name: µ-Conotoxin KIIIA
Chemical Name: µ-Conotoxin KIIIA
CAS Number: 884469-67-4
Molecular Formula: C₇₀H₁₀₆N₂₈O₂₂S₆
Molecular Weight: 1884.16
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2023-10-05 16:55:49
Modify Date: 2024-01-05 17:57:32
μ-Conotoxin KIIIA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. μ-Conotoxin KIIIA blocks mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2).μ-Conotoxin KIIIA can be used for research of pain[1][2].

Name	µ-Conotoxin KIIIA

Description	μ-Conotoxin KIIIA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. μ-Conotoxin KIIIA blocks mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2).μ-Conotoxin KIIIA can be used for research of pain[1][2].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Inflammation/Immunology
Target	NaV1.2 Channel[2]
References	[1]. Khoo KK,et al. Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion. Biochemistry. 2009 Feb 17;48(6):1210-9. [2]. Pan X, Li Z, et al. Molecular basis for pore blockade of human Na+ channel Nav1.2 by the μ-conotoxin KIIIA. Science. 2019 Mar 22;363(6433):1309-1313.

Molecular Formula	C₇₀H₁₀₆N₂₈O₂₂S₆
Molecular Weight	1884.16