2810747-78-3

2810747-78-3 structure

Name: BLU0588
Chemical Name: BLU0588
CAS Number: 2810747-78-3
Molecular Formula: C₂₆H₂₅N₅O
Molecular Weight: 423.51
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK PKA
Create Date: 2023-09-22 23:15:58
Modify Date: 2024-04-08 16:48:27
BLU0588 is an orally active, potent and selective PRKACA (protein kinase cAMP-activated catalytic subunit alpha) kinase inhibitor, with an IC50 of 1 nM and dissociation constant (Kd) of 4 nM. BLU0588 can be used for fibrolamellar carcinoma (FLC) research[1].

Name	BLU0588

Description	BLU0588 is an orally active, potent and selective PRKACA (protein kinase cAMP-activated catalytic subunit alpha) kinase inhibitor, with an IC50 of 1 nM and dissociation constant (Kd) of 4 nM. BLU0588 can be used for fibrolamellar carcinoma (FLC) research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA Signaling Pathways >> Stem Cell/Wnt >> PKA
Target	IC50: 1 nM (PRKACA)[1]
References	[1]. Stefanie S. Schalm, et al. Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma. Gastro Hep Advances. Volume 2, Issue 3, 2023, Pages 307-321.

Molecular Formula	C₂₆H₂₅N₅O
Molecular Weight	423.51