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2408994-22-7

2408994-22-7 structure

2408994-22-7 structure

Name: BET-IN-15
Chemical Name: BET-IN-15
CAS Number: 2408994-22-7
Molecular Formula: C₂₁H₁₈F₂N₄O₃S
Molecular Weight: 444.45
Catalog: Signaling Pathways Epigenetics Epigenetic Reader Domain
Create Date: 2023-09-24 09:25:14
Modify Date: 2024-01-13 17:14:00
BET-IN-15 (compound 1) is a potent and orally active BET inhibitor with IC50 values of 0.64, 0.25 nM for BRD4-BD1, BRD4-BD2, respectively. BET-IN-15 shows antiproliferative activity[1].

Name	BET-IN-15

Description	BET-IN-15 (compound 1) is a potent and orally active BET inhibitor with IC50 values of 0.64, 0.25 nM for BRD4-BD1, BRD4-BD2, respectively. BET-IN-15 shows antiproliferative activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Epigenetic Reader Domain
Target	BRD4-BD1:0.64 nM (IC50) BRD4-BD2:0.25 nM (IC50)
References	[1]. WenWei Xu, et al. Crystal form and salt form of bromine domain protein inhibitor and preparation method therefor. WO2021143922A1.

Molecular Formula	C₂₁H₁₈F₂N₄O₃S
Molecular Weight	444.45

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