445000-45-3

445000-45-3 structure

Name: BBT
Chemical Name: BBT
CAS Number: 445000-45-3
Molecular Formula: C₁₈H₁₂BrNO₂S
Molecular Weight: 386.26
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2023-10-24 17:06:09
Modify Date: 2025-08-19 18:11:17
BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT exhibits anti-hyperglycemia activity, and protects β-cells from cytokine- or streptozotocin (STZ)-induced cell death in type 2 diabetes models. BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/CaMK2 pathway[1].

Name	BBT

Description	BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT exhibits anti-hyperglycemia activity, and protects β-cells from cytokine- or streptozotocin (STZ)-induced cell death in type 2 diabetes models. BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/CaMK2 pathway[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Metabolic Disease
Target	L-type voltage-dependent Ca2+ channel/CaMK2[1]
References	[1]. Yao XG, et al. BBT improves glucose homeostasis by ameliorating 尾-cell dysfunction in type 2 diabetic mice. J Endocrinol. 2015 Mar;224(3):327-41.

Molecular Formula	C₁₈H₁₂BrNO₂S
Molecular Weight	386.26