2259884-03-0

2259884-03-0 structure

Name: mazdutide
Chemical Name: Mazdutide
CAS Number: 2259884-03-0
Molecular Formula: C₂₀₇H₃₁₇N₄₅O₆₅
Molecular Weight: 4476
Create Date: 2023-08-10 11:55:27
Modify Date: 2026-07-16 18:42:52
Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a glucagon-like peptide-1 (GLP-1R)/glucagon receptor GCGR co-agonist. Mazdutide has safety and tolerability, and it can be used for research in obesity and type 2 diabetes (T2D)[1][2].

Name	Mazdutide

Description	Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a glucagon-like peptide-1 (GLP-1R)/glucagon receptor GCGR co-agonist. Mazdutide has safety and tolerability, and it can be used for research in obesity and type 2 diabetes (T2D)[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Chen T, et al. The Design and Optimization of Monomeric Multitarget Peptides for the Treatment of Multifactorial Diseases. J Med Chem. 2022 Mar 10;65(5):3685-3705. [2]. Jiang H, et al. A phase 1b randomised controlled trial of a glucagon-like peptide-1 and glucagon receptor dual agonist IBI362 (LY3305677) in Chinese patients with type 2 diabetes. Nat Commun. 2022 Jun 24;13(1):3613.