13728-56-8
13728-56-8 structure
- Name: HIV-1 Nef-IN-1
- Chemical Name: 4-phenanthren-3-ylbutanoic acid
- CAS Number: 13728-56-8
- Molecular Formula: C18H16O2
- Molecular Weight: 264.31800
- Catalog: Signaling Pathways Anti-infection HIV
- Create Date: 2016-09-20 06:07:26
- Modify Date: 2025-08-25 20:15:38
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HIV-1 Nef-IN-1 is an HIV-1 Nef protein inhibitor that efficiently competes for Nef-SH3Hck interactions with a Kd of 6.7 μM[1].
| Name | 4-phenanthren-3-ylbutanoic acid |
|---|---|
| Synonyms |
3-Phenanthrenebutanoicacid
3-Phenanthrenebutyric acid Compound D11 |
| Description | HIV-1 Nef-IN-1 is an HIV-1 Nef protein inhibitor that efficiently competes for Nef-SH3Hck interactions with a Kd of 6.7 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
HIV-1 Nef:6.7 μM (Kd) |
| In Vitro | HIV-1 Nef-IN-1 (Compound D11; 20 μM) inhibits cell viability of COS7 cells, and the cell inhibition rate is 63.2%[1]. |
| References |
| Density | 1.211g/cm3 |
|---|---|
| Boiling Point | 487.2ºC at 760mmHg |
| Molecular Formula | C18H16O2 |
| Molecular Weight | 264.31800 |
| Flash Point | 383.7ºC |
| Exact Mass | 264.11500 |
| PSA | 37.30000 |
| LogP | 4.40030 |
| Vapour Pressure | 2.63E-10mmHg at 25°C |
| Index of Refraction | 1.678 |
| HS Code | 2916399090 |
|---|
|
~%
13728-56-8 |
| Literature: Newman,M.S. et al. Journal of Organic Chemistry, 1966 , vol. 31, p. 4293 - 4296 |
| Precursor 1 | |
|---|---|
| DownStream 4 | |
![Benz[a]anthracene-8-acetic acid structure](https://image.chemsrc.com/caspic/036/13728-58-0.png)
![benzo[j]aceanthrylene structure](https://image.chemsrc.com/caspic/057/202-33-5.png)
![Benz[a]anthracen-8(9H)-one, 10,11-dihydro- structure](https://image.chemsrc.com/caspic/204/5472-20-8.png)
| HS Code | 2916399090 |
|---|---|
| Summary | 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |