76472-87-2

76472-87-2 structure

Name: Kuwanon H
Chemical Name: kuwanone H
CAS Number: 76472-87-2
Molecular Formula: C₄₅H₄₄O₁₁
Molecular Weight: 760.82400
Catalog: Signaling Pathways GPCR/G Protein Bombesin Receptor
Create Date: 2016-03-18 02:46:38
Modify Date: 2025-08-25 16:16:24
Kuwanon H is a flavonoid isolated from Morus bombycis, which acts as a potent non-peptide bombesin receptor antagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP to GRP-preferring recepotr, with a Ki value of 290 nM in cells[1].

Name	kuwanone H
Synonyms	Albanin G Alvanin G kuwanon H Moracenin A NSC 356889

Description	Kuwanon H is a flavonoid isolated from Morus bombycis, which acts as a potent non-peptide bombesin receptor antagonist. Kuwanon H selectively inhibits binding of gastrin releasing peptide CRP to GRP-preferring recepotr, with a Ki value of 290 nM in cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Bombesin Receptor
Target	Ki: 290 nM (GRP-preferring recepotr)[1]
References	[1]. Mihara S, et al. Non-peptide bombesin receptor antagonists, kuwanon G and H, isolated from mulberry. Biochem Biophys Res Commun. 1995 Aug 15;213(2):594-9.