31447-29-7

31447-29-7 structure

Name: Linoleic acid-d2
Chemical Name: Linoleic acid-d2
CAS Number: 31447-29-7
Molecular Formula: C₁₈H₃₀D₂O₂
Molecular Weight: 282.46
Catalog: Research Areas Metabolic Disease
Create Date: 2023-07-08 19:22:48
Modify Date: 2024-01-12 12:15:45
Linoleic Acid-d2 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism[1][2].

Name	Linoleic acid-d2

Description	Linoleic Acid-d2 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism[1][2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Jay Whelan. Linoleic Acid. Adv Nutr. 2013 May; 4(3): 311–312. [3]. Yuan T, et al. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. Int J Clin Exp Pathol. 2015 May 1;8(5):5044-52.

Molecular Formula	C₁₈H₃₀D₂O₂
Molecular Weight	282.46