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2396382-78-6

2396382-78-6 structure

2396382-78-6 structure

Name: HIV-1 capsid inhibitor 1
Chemical Name: HIV-1 capsid inhibitor 1
CAS Number: 2396382-78-6
Molecular Formula: C₃₄H₃₁FN₆O₄
Molecular Weight: 606.65
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2023-07-29 18:25:32
Modify Date: 2024-01-13 22:45:23
HIV-1 capsid inhibitor 1 is a potent HIV-1 Capsid inhibitor with an EC50 value of 3.13 µM. HIV-1 capsid inhibitor 1 shows antiviral activities[1].

Name	HIV-1 capsid inhibitor 1

Description	HIV-1 capsid inhibitor 1 is a potent HIV-1 Capsid inhibitor with an EC50 value of 3.13 µM. HIV-1 capsid inhibitor 1 shows antiviral activities[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1:3.13 μM (EC50)
In Vitro	HIV-1 capsid inhibitor 1 (compound 6a-9) 在 TZM-bl 细胞中表现出抗 HIV 活性，EC50 值为 3.13 µM，CC50 值为 >16.48 µM[1]。 HIV-1 capsid inhibitor 1 在 HIV-1 NL4-3 生命周期的早期和晚期显示出抗病毒活性，IC50 分别为 8.18、0.32 µM<[1]。 HIV-1 capsid inhibitor 1 在人肝微粒体和血浆中表现出代谢稳定性[1]。
References	[1]. Sun L, et al. Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities. Eur J Med Chem. 2020 Mar 15;190:112085.

Molecular Formula	C₃₄H₃₁FN₆O₄
Molecular Weight	606.65

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