2414056-34-9
2414056-34-9 structure
- Name: HER2-IN-13
- Chemical Name: HER2-IN-13
- CAS Number: 2414056-34-9
- Molecular Formula: C26H23ClF2N8O3
- Molecular Weight: 568.96
- Catalog: Signaling Pathways JAK/STAT Signaling EGFR
- Create Date: 2023-05-31 15:49:21
- Modify Date: 2025-08-27 20:53:09
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HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1].
| Name | HER2-IN-13 |
|---|
| Description | HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
HER2:8 nM (IC50) EGFR (WT):0.40 μM (IC50) hERG:13.3 μM (IC50) |
| In Vitro | HER2-IN-13 (Compound 33) 抑制 hERG 通道，IC50 为 13.3 μM[1]。 |
| References |
[1]. Ding Zhou, et al. Quinazoline derivatives as antitumor agents. Patent WO2020057511A1. |
| Molecular Formula | C26H23ClF2N8O3 |
|---|---|
| Molecular Weight | 568.96 |