103963-38-8

103963-38-8 structure

Name: Ganoderic acid S
Chemical Name: Ganoderic acid S
CAS Number: 103963-38-8
Molecular Formula: C₃₂H₄₈O₅
Molecular Weight: 512.72
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-08-14 02:07:33
Modify Date: 2024-01-14 09:48:21
Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. Ganoderic acid S can induce apoptosis in HeLa cells through the mitochondria pathway[1].

Name	Ganoderic acid S

Description	Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. Ganoderic acid S can induce apoptosis in HeLa cells through the mitochondria pathway[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
In Vitro	Ganoderic acid S (0, 39.1, 97.7 μM; 12 h) 在 HeLa 细胞中导致细胞周期停滞在 S 期[1]。 Ganoderic acid S 剂量依赖性地导致线粒体膜电位的崩溃。Ganoderic acid S 诱导细胞色素 c 从线粒体大量释放到 HeLa 细胞的胞质溶胶中[1]。 Cell Cycle Analysis[1] Cell Line: HeLa cells Concentration: 0, 39.1, 97.7 μM Incubation Time: 12 h Result: Caused cell cycle arrest in the S phase.
References	[1]. Liu RM, et al. Ganoderic acid Mf and S induce mitochondria mediated apoptosis in human cervical carcinoma HeLa cells. Phytomedicine. 2011 Mar 15;18(5):349-55.

Molecular Formula	C₃₂H₄₈O₅
Molecular Weight	512.72