2690312-65-1
2690312-65-1 structure
- Name: ASR-488
- Chemical Name: ASR-488
- CAS Number: 2690312-65-1
- Molecular Formula: C33H40O7S
- Molecular Weight: 580.73
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2023-10-06 11:53:53
- Modify Date: 2024-01-11 11:15:16
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ASR-488 activates the mRNA-binding protein CPEB1, induces apoptosis and inhibits bladder cancer growth[1].
| Name | ASR-488 |
|---|
| Description | ASR-488 activates the mRNA-binding protein CPEB1, induces apoptosis and inhibits bladder cancer growth[1]. |
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| Related Catalog | |
| In Vitro | ASR-488 (0.2-12.5 µM，24-72 h) 可有效诱导细胞凋亡信号并显着抑制 TCCSUP 和 HT1376 细胞的生长[1]。 Cell Proliferation Assay[1] Cell Line: BCa cell lines TCCSUP and HT1376 Concentration: 0.2-12.5 µM Incubation Time: 24, 48 and 72 h Result: Showed that the IC 50 of TCCSUP was 800, 480 and 450 nM at different time periods of 24, 48 and 72 hours, and the IC 50 of HT1376 was 1.28 µM, 750 and 850 nM, respectively. Caused a downregulation of p65 and Bcl-2 expression and a marked increase in apoptosis in TCCSUP and HT1376 cells. |
| References |
| Molecular Formula | C33H40O7S |
|---|---|
| Molecular Weight | 580.73 |