1448188-69-9

1448188-69-9 structure
1448188-69-9 structure
  • Name: VL285 Phenol
  • Chemical Name: VL285 Phenol
  • CAS Number: 1448188-69-9
  • Molecular Formula: C29H32N4O5S
  • Molecular Weight: 548.65
  • Catalog: Research Areas Cancer
  • Create Date: 2023-04-25 14:43:19
  • Modify Date: 2024-01-16 11:55:29
  • VL285 Phenol is a VL285 analogue with Phenol group. VL285, a small molecule VHL ligand, can be served as a degrader for HaloPROTAC3 synthesis.VL285 degrades HaloTag7 fusion proteins (IC50=0.34 μM)[1].

Name VL285 Phenol
Description VL285 Phenol is a VL285 analogue with Phenol group. VL285, a small molecule VHL ligand, can be served as a degrader for HaloPROTAC3 synthesis.VL285 degrades HaloTag7 fusion proteins (IC50=0.34 μM)[1].
Related Catalog
In Vitro VL285(100 μM;24 小时)减弱 HaloPROTAC3 诱导 GFP-HaloTag7 降解的能力[1]。
References

[1]. Buckley DL, et al. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins. ACS Chem Biol. 2015 Aug 21;10(8):1831-7.  

Molecular Formula C29H32N4O5S
Molecular Weight 548.65