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1218993-18-0

1218993-18-0 structure

1218993-18-0 structure

Name: TRIA-662-d3
Chemical Name: TRIA-662-d3
CAS Number: 1218993-18-0
Molecular Formula: C₇H₆D₃ClN₂O
Molecular Weight: 175.63
Catalog: Research Areas Metabolic Disease
Create Date: 2023-07-08 15:52:35
Modify Date: 2025-08-26 10:03:05
TRIA-662-d3 is the deuterium labeled TRIA-662[1]. TRIA-662 (1-Methylnicotinamide chloride) is an endogenous metabolite. TRIA-662 shows antithrombotic and anti-inflammatory activities[2].

Name	TRIA-662-d3

Description	TRIA-662-d3 is the deuterium labeled TRIA-662[1]. TRIA-662 (1-Methylnicotinamide chloride) is an endogenous metabolite. TRIA-662 shows antithrombotic and anti-inflammatory activities[2].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. A M Kolodziejczyk, et al. Nanomechanical sensing of the endothelial cell response to anti-inflammatory action of 1-methylnicotinamide chloride. Int J Nanomedicine. 2013;8:2757-67.

Molecular Formula	C₇H₆D₃ClN₂O
Molecular Weight	175.63

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