68261-19-8

68261-19-8 structure

68261-19-8 structure

Name: L-Aspartic acid-C13-1
Chemical Name: L-Aspartic acid-C13-1
CAS Number: 68261-19-8
Molecular Formula: C₃₁₃CH₇NO₄
Molecular Weight: 134.10
Catalog: Research Areas Cardiovascular Disease
Create Date: 2023-05-13 18:52:19
Modify Date: 2024-04-06 11:15:56
L-Aspartic acid-13C-1 is the deuterium labeled L-Aspartic acid[1]. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly[2][3].

Name	L-Aspartic acid-C13-1

Description	L-Aspartic acid-13C-1 is the deuterium labeled L-Aspartic acid[1]. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly[2][3].
Related Catalog	Research Areas >> Cardiovascular Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11. [3]. Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug23(4):397-406.

Molecular Formula	C₃₁₃CH₇NO₄
Molecular Weight	134.10