1391727-24-4

1391727-24-4 structure

Name: Ipafricept
Chemical Name: Ipafricept
CAS Number: 1391727-24-4
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Stem Cell/Wnt Wnt
Create Date: 2023-05-23 10:01:27
Modify Date: 2024-01-05 17:16:42
Ipafricept (OMP-54F28; FZD8-Fc) is the first class of recombinant fusion proteins, consisting of the extracellular portion of the human fried-8 receptor fused to the Fc fragment of human IgG1 binding to the Wnt ligand. Ipafricept shows solid tumor inhibition activity, with well tolerance[1].

Name	Ipafricept

Description	Ipafricept (OMP-54F28; FZD8-Fc) is the first class of recombinant fusion proteins, consisting of the extracellular portion of the human fried-8 receptor fused to the Fc fragment of human IgG1 binding to the Wnt ligand. Ipafricept shows solid tumor inhibition activity, with well tolerance[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Wnt
Target	Wnt ligand[1]
References	[1]. Jimeno A, et al. A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors. Clin Cancer Res. 2017 Dec 15;23(24):7490-7497.

No Any Chemical & Physical Properties