510-18-9

510-18-9 structure
510-18-9 structure
  • Name: Acetomycin
  • Chemical Name: 2(3H)-Furanone, 3-acetyl-5-(acetyloxy)dihydro-3,4-dimethyl
  • CAS Number: 510-18-9
  • Molecular Formula: C10H14O5
  • Molecular Weight: 214.22
  • Catalog: Research Areas Cancer
  • Create Date: 2016-06-10 11:58:02
  • Modify Date: 2024-01-24 20:19:35
  • Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661[1].

Name 2(3H)-Furanone, 3-acetyl-5-(acetyloxy)dihydro-3,4-dimethyl
Synonyms acetomycin
Description Acetomycin is an antibiotic. Acetomycin inhibits the growth of CT-8 human colon adenocarcinoma cells (IC50: 1.5 μg/mL) and L1210 murine leukemia cells (IC50: 2.2 μg/mL). Acetomycin can be isolated from actinomycete WP-2661[1].
Related Catalog
References

[1]. Mamber SW, et al. Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivo. J Antibiot (Tokyo). 1987 Jan;40(1):73-6.  

Density 1.18g/cm3
Boiling Point 336.2ºC at 760mmHg
Molecular Formula C10H14O5
Molecular Weight 214.22
Flash Point 148.9ºC
Exact Mass 214.08400
PSA 69.67000
LogP 0.66380
Index of Refraction 1.466

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AL2850000
CHEMICAL NAME :
Acetomycin
CAS REGISTRY NUMBER :
510-18-9
BEILSTEIN REFERENCE NO. :
0174279
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H14-O5
MOLECULAR WEIGHT :
214.24
WISWESSER LINE NOTATION :
T5OVTJ CV1 C1 D1 EOV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 2,905,1978
HS Code 2932190090
HS Code 2932190090
Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%