1403496-40-1

1403496-40-1 structure

Name: Fotagliptin benzoate
Chemical Name: Fotagliptin benzoate
CAS Number: 1403496-40-1
Molecular Formula: C₂₄H₂₅FN₆O₃
Molecular Weight: 464.49
Catalog: Signaling Pathways Metabolic Enzyme/Protease Dipeptidyl Peptidase
Create Date: 2023-04-17 12:42:18
Modify Date: 2024-04-11 17:44:39
Fotagliptin benzoate is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM). Fotagliptin benzoate displays great security in rat and dog. Fotagliptin benzoate can be used for Type 2 diabetes mellitus research[1].

Name	Fotagliptin benzoate

Description	Fotagliptin benzoate is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM). Fotagliptin benzoate displays great security in rat and dog. Fotagliptin benzoate can be used for Type 2 diabetes mellitus research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Dipeptidyl Peptidase Research Areas >> Metabolic Disease
Target	DPP-4:22.7 nM (IC50)
In Vivo	Fotagliptin benzoate (33 mg/kg 或 110 mg/kg) 在不同剂量下对大鼠和狗是安全的[1]。
References	[1]. Wang Z, et al. Development and validation of a UPLC-MS/MS method for simultaneous determination of fotagliptin and its two major metabolites in human plasma and urine. Bioanalysis. 2017 Feb;9(4):381-393.

Molecular Formula	C₂₄H₂₅FN₆O₃
Molecular Weight	464.49