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2833706-13-9

2833706-13-9 structure

2833706-13-9 structure

Name: FGFR3-IN-4
Chemical Name: FGFR3-IN-4
CAS Number: 2833706-13-9
Molecular Formula: C₂₆H₂₄ClN₇O
Molecular Weight: 485.97
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
Create Date: 2023-04-14 16:23:19
Modify Date: 2024-01-06 00:03:38
FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].

Name	FGFR3-IN-4

Description	FGFR3-IN-4 is a selective FGFR3 inhibitor, with an IC50 value of less than 50 nM. FGFR3-IN-4 is at least 10 fold more selective for FGFR3 than for FGFR1[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR
Target	FGFR3:< 50 nM (IC50)
In Vitro	FGFR3 (example 297) 抑制 FGFR3 活性，IC50 值小于 50 nM[1]。
References	[1]. Abraham, et al. Preparation of substituted pyrazolo[1,5-a]pyridine-3-carbonitriles and imidazo[1,2-a]pyridine-3-carbonitriles as FGFR3 inhibitors. WO2022187443.

Molecular Formula	C₂₆H₂₄ClN₇O
Molecular Weight	485.97