288392-69-8
288392-69-8 structure
- Name: Siplizumab
- Chemical Name: Siplizumab
- CAS Number: 288392-69-8
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Inflammation/Immunology
- Create Date: 2023-03-09 06:45:17
- Modify Date: 2025-08-26 19:40:52
-
Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody against CD2. Siplizumab depletes T cells, decreases T cell activation, inhibites T cell proliferation and enriches naïve and bona fide regulatory T cells[1].
| Name | Siplizumab |
|---|
| Description | Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody against CD2. Siplizumab depletes T cells, decreases T cell activation, inhibites T cell proliferation and enriches naïve and bona fide regulatory T cells[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Siplizumab (MEDI-507; 0.00001-10 nM) 结合 FcγR 并诱导信号转导[1]。 Siplizumab (0.0001-10 μg/mL) 介导细胞耗竭并降低 T 细胞增殖[1]。 |
| References |
| No Any Chemical & Physical Properties |