2873418-48-3

2873418-48-3 structure

2873418-48-3 structure

Name: Tyrosinase-IN-10
Chemical Name: Tyrosinase-IN-10
CAS Number: 2873418-48-3
Molecular Formula: C₁₆H₁₂O₄
Molecular Weight: 268.26
Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
Create Date: 2023-01-26 19:13:52
Modify Date: 2024-04-06 19:23:23
Tyrosinase-IN-10 (Compound 23) is a partially competitive tyrosinase inhibitor with an IC50 of 1.6 μM against tyrosinase activity from human melanoma cell lysates[1].

Name	Tyrosinase-IN-10

Description	Tyrosinase-IN-10 (Compound 23) is a partially competitive tyrosinase inhibitor with an IC50 of 1.6 μM against tyrosinase activity from human melanoma cell lysates[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase
Target	IC50: 1.6 μM (human tyrosinase)[1]
In Vitro	Tyrosinase-IN-10 (Compound 23) (0-100 μM; 96 h) 抑制 MNT-1 全细胞黑素生成，IC50 为 29 μM, 对 MNT-1 的细胞毒性 CC50 为 91 μM[1]。 Cell Cytotoxicity Assay[1] Cell Line: MNT-1 cells Concentration: 0-100 μM Incubation Time: 96 h Result: Showed cytotoxicity with a CC50 of 91 μM.
References	[1]. Roulier B, et al. Resorcinol-based hemiindigoid derivatives as human tyrosinase inhibitors and melanogenesis suppressors in human melanoma cells. Eur J Med Chem. 2023 Jan 15;246:114972.

Molecular Formula	C₁₆H₁₂O₄
Molecular Weight	268.26