929555-18-0

929555-18-0 structure
929555-18-0 structure
  • Name: Scospondistatin
  • Chemical Name: Scospondistatin
  • CAS Number: 929555-18-0
  • Molecular Formula: C81H127N27O30S2
  • Molecular Weight: 2023.17
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2023-03-13 18:18:26
  • Modify Date: 2025-08-26 09:04:20
  • Scospondistatin is an anti-angiogenic peptide that can inhibit proliferation and migration of human umbilical vein endothelial cells in vitro[1].

Name Scospondistatin
Description Scospondistatin is an anti-angiogenic peptide that can inhibit proliferation and migration of human umbilical vein endothelial cells in vitro[1].
Related Catalog
In Vitro Scospondistatin (0.01-40 μg/mL; 3 d) 以剂量依赖的方式抑制人脐静脉内皮细胞 (HUVECs) 增殖[1]。 Scospondistatin (30 μg/mL; 20 h) 在 VEGF 存在时,显著抑制 HUVECs 的迁移[1]。 Cell Proliferation Assay[1] Cell Line: HUVECs Concentration: 0.01, 0.1, 1, 10, 20, 30 and 40 μg/mL Incubation Time: 3 days Result: Showed a monotonic dose response, with the anti-proliferative activity increasing with increasing the peptide concentration. Cell Migration Assay [1] Cell Line: HUVECs Concentration: 1, 10 and 30 μg/mL Incubation Time: 20 h Result: Significantly inhibited the migration of HUVECs in the presence of VEGF at 30 μg/mL.
References

[1]. Karagiannis ED, et al. Anti-angiogenic peptides identified in thrombospondin type I domains. Biochem Biophys Res Commun. 2007 Jul 20;359(1):63-9.  

Molecular Formula C81H127N27O30S2
Molecular Weight 2023.17
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