331243-22-2

331243-22-2 structure
331243-22-2 structure
  • Name: Pascolizumab
  • Chemical Name: Pascolizumab
  • CAS Number: 331243-22-2
  • Molecular Formula:
  • Molecular Weight:
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2023-02-08 10:14:33
  • Modify Date: 2025-09-02 06:02:52
  • Pascolizumab (SB-240683) is a humanized anti-IL-4 monoclonal antibody. Pascolizumab has the potential for the research of asthma[1].

Name Pascolizumab
Description Pascolizumab (SB-240683) is a humanized anti-IL-4 monoclonal antibody. Pascolizumab has the potential for the research of asthma[1].
Related Catalog
In Vitro Pascolizumab 结合 IL-4 可抑制 IL-4 与 IL-4 受体的 α 链相互作用[1]。 Pascolizumab (0-10000 pM; 3 days) 显示出抗增殖活性,对 T 细胞和扁桃体 B 细胞的 IC50 值分别为 157、377 pM[1]。 Cell Proliferation Assay[1] Cell Line: human or monkey T cells Concentration: 0-10000 pM Incubation Time: 3 days Result: Inhibited the response of human and monkey T cells to recombinant monkey IL-4 (2 ng/ml) with IC50 values of 268 pM and 587 pM, respectively.
References

[1]. Hart TK, et al. Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma. Clin Exp Immunol. 2002 Oct;130(1):93-100.  

No Any Chemical & Physical Properties
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