952306-80-8

952306-80-8 structure

952306-80-8 structure

Name: hCAII-IN-8
Chemical Name: hCAII-IN-8
CAS Number: 952306-80-8
Molecular Formula: C₁₅H₁₆N₂O₅S
Molecular Weight: 336.36
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2023-01-30 15:58:51
Modify Date: 2024-04-03 16:07:42
hCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC50 value of 0.18 μM against hCA II[1].

Name	hCAII-IN-8

Description	hCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC50 value of 0.18 μM against hCA II[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	hCA II:0.18 μM (IC50)
In Vitro	hCAII-IN-8 (化合物 9; 100 μM; 24-48 小时) 与对照相比，对 HEK-293 T 细胞没有细胞毒性，细胞活力 >90%[1]。
References	[1]. Zahid Hussain, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264.

Molecular Formula	C₁₅H₁₆N₂O₅S
Molecular Weight	336.36