2419087-87-7
2419087-87-7 structure
- Name: Zamerovimab
- Chemical Name: Zamerovimab
- CAS Number: 2419087-87-7
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Infection
- Create Date: 2023-01-19 18:38:57
- Modify Date: 2025-08-27 13:21:43
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Zamerovimab (CTB011; SYN023) is a mixture of human monoclonal antibodies consisting of CTB011 and CTB012. Zamerovimab binds to non-overlapping epitopes on rabies virus (RABV) glycoprotein, where CTB011 binds to antigenic site III. Zamerovimab can be used in rabies studies[1].
| Name | Zamerovimab |
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| Description | Zamerovimab (CTB011; SYN023) is a mixture of human monoclonal antibodies consisting of CTB011 and CTB012. Zamerovimab binds to non-overlapping epitopes on rabies virus (RABV) glycoprotein, where CTB011 binds to antigenic site III. Zamerovimab can be used in rabies studies[1]. |
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| Related Catalog | |
| In Vitro | Zamerovimab (CTB011; SYN023) (0.001-100 μg/mL, 4 h) 在 CVS 感染的 BSR 细胞中，以剂量依赖性方式诱导细胞毒性，促进病毒清除，也表明细胞毒性与表达 G 蛋白的细胞特异性相关，而这些细胞被 CTB011 靶向[1]。 |
| In Vivo | Zamerovimab (CTB011; SYN023) (0.03-1.0 mg/kg，右腓肠肌注射，一次，35 天) 可以以剂量依赖性方式增加感染了狂犬病病毒RABV BD06 的叙利亚仓鼠的存活率，在剂量分别为 0.03、0.1、0.3、1.0 mg/kg 时，存活率分别为 58%，83%，100% 和 100%[1]。 |
| References |
| No Any Chemical & Physical Properties |