2420564-02-7
2420564-02-7 structure
- Name: Tixagevimab
- Chemical Name: Tixagevimab
- CAS Number: 2420564-02-7
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Anti-infection SARS-CoV
- Create Date: 2023-01-28 17:25:22
- Modify Date: 2025-09-04 00:24:20
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Tixagevimab (AZD8895) is a human monoclonal antibody that targets the SARS-CoV-2 receptor binding domain (RBD). It exhibits neutralizing activity against SARS-CoV-2 by binding to the RBD and the S-glycoprotein ectodomain and blocking S-glycoprotein-mediated binding to the receptor[1].
| Name | Tixagevimab |
|---|
| Description | Tixagevimab (AZD8895) is a human monoclonal antibody that targets the SARS-CoV-2 receptor binding domain (RBD). It exhibits neutralizing activity against SARS-CoV-2 by binding to the RBD and the S-glycoprotein ectodomain and blocking S-glycoprotein-mediated binding to the receptor[1]. |
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| Related Catalog | |
| In Vivo | Tixagevimab 可以与 Cilgavimab 组合，形成 AZD7442，AZD7442（2，4 或 16 mg/kg，静脉注射）在感染 G61 菌株的仓鼠以及在感染了 Omicron 变种的仓鼠中，可以导致肺部感染滴度和病毒 RNA 水平呈剂量依赖性下降，且与 2 mg/kg 剂量的动物相比，16 mg/kg 剂量的感染滴度显著降低[2]。 |
| References |
| No Any Chemical & Physical Properties |