Shanghai Nianxing Industrial Co., Ltd
China
Product Name: timolumab
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Purity: 95.0%
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1073538-99-4

1073538-99-4 structure

1073538-99-4 structure

Name: Timolumab
Chemical Name: Timolumab
CAS Number: 1073538-99-4
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Inflammation/Immunology
Create Date: 2023-03-11 12:10:45
Modify Date: 2025-08-20 17:56:35
Timolumab (BTT1023 ), a recombinant fully human monoclonal antibody that specifically binds VAP-1. Timolumab (BTT1023 ) could be used in the study of chronic inflammatory diseases[1][2].

Name	Timolumab

Description	Timolumab (BTT1023 ), a recombinant fully human monoclonal antibody that specifically binds VAP-1. Timolumab (BTT1023 ) could be used in the study of chronic inflammatory diseases[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology
In Vitro	Timolumab (BTT1023 ) binds to human VAP-1, thereby blocking its function as an adhesion molecule. It also recognizes VAP-1 of other primates and rabbits but does not cross-react with rat or mouse. Timolumab (BTT1023 ) is potentially useful for the treatment and in vivo imaging of inflammatory conditions such as rheumatoid arthritis[2].
References	[1]. Ahmad H Ali, et al. Novel treatments in primary sclerosing cholangitis. Clin Liver Dis (Hoboken). 2016 Nov 30;8(5):132-135. [2]. Takayuki Inoue, et al. Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema. Bioorg Med Chem. 2013 Mar 1;21(5):1219-33. [3]. Anu Autio, et al. Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein-1-positive vasculature in inflammation. J Nucl Med. 2013 Aug;54(8):1315-9.

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