2417370-48-8

2417370-48-8 structure

Name: (S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA
Chemical Name: (S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA
CAS Number: 2417370-48-8
Molecular Formula: C₃₈H₅₆F₃N₅O₁₃S₃
Molecular Weight: 944.07
Catalog: Signaling Pathways PROTAC E3 Ligase Ligand-Linker Conjugate
Create Date: 2023-01-11 11:27:05
Modify Date: 2024-04-06 09:37:28
(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based ligand and 3-unit PEG linker used in PROTAC technology[1].

Name	(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA

Description	(S,R,S)-AHPC-3-methylbutanyl acetate-methanesulfonothioate-PEG3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based ligand and 3-unit PEG linker used in PROTAC technology[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
References	[1]. Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.

Molecular Formula	C₃₈H₅₆F₃N₅O₁₃S₃
Molecular Weight	944.07