1092658-06-4

1092658-06-4 structure

1092658-06-4 structure

Name: Ensituximab
Chemical Name: Ensituximab
CAS Number: 1092658-06-4
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Cancer
Create Date: 2023-01-11 09:06:39
Modify Date: 2024-02-03 17:37:04
Ensituximab (NEO-102; NPC-1C) is a chimeric monoclonal IgG1 antibody targeting a variant of MUC5AC. Ensituximab shows specificity to colorectal and pancreatic cancer[1][2].

Name	Ensituximab

Description	Ensituximab (NEO-102; NPC-1C) is a chimeric monoclonal IgG1 antibody targeting a variant of MUC5AC. Ensituximab shows specificity to colorectal and pancreatic cancer[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Ensituximab (NPC-1C) 是一种嵌合 IgG1 单克隆抗体，在结合其靶标后促进抗体依赖性细胞的细胞毒性，MUC5AC 是一种肿瘤特异性变体，一种由结直肠癌 (CRC) 和胰腺癌特异性表达的抗原[1]。
References	[1]. Richard D Kim, et al. Phase II Study of Ensituximab, a Novel Chimeric Monoclonal Antibody, in Adults with Unresectable, Metastatic Colorectal Cancer. Clin Cancer Res. 2020 Jul 15;26(14):3557-3564. [2]. Julian A Marin-Acevedo, et al. Cancer immunotherapy beyond immune checkpoint inhibitors. J Hematol Oncol. 2018 Jan 12;11(1):8.

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